Glucose Fluctuations during Gestation: An Additional Tool for Monitoring Pregnancy Complicated by Diabetes

Table 1

Correlations between indicators of glucose variability and mean glucose value (mean value) obtained in the 2nd trimester and with HbA1c obtained in the 3rd trimester of pregnancy. Pearson’s analysis was performed on type 1 diabetes (Table 1(a)) and GDM patients (Table 1(b)).

(a)  

		MAGE 2	SD 2	IQR 2	CONGA 1-2	LBGI 2	HBGI 2
Mean value 2	Correlation	0.50*	0.62*	0.49*	0.28	−0.61*	0.93*
	𝑃 value	0.02	<0.01	0.03	0.24	<0.01	<0.001
MAGE 2	Correlation		0.86*	0.74*	0.67*	0.48	0.36
	𝑃 value		<0.001	<0.001	0.00	0.11	0.13
SD 2	Correlation			0.78*	0.84*	0.29	0.62*
	𝑃 value			<0.001	<0.001	0.22	<0.01
IQR 2	Correlation				0.54*	0.18	0.59*
	𝑃 value				0.01	0.43	<0.01
CONGA 1-2	Correlation					−0.06	0.55*
	𝑃 value					0.81	0.01
LBGI 2	Correlation						−0.50*
	𝑃 value						0.02
HbA1c 3	Correlation	0.14	0.14	0.09	0.38	−0.22	0.36
	𝑃 value	0.60	0.62	0.74	0.15	0.41	0.17

(b)  

		MAGE 2	SD 2	IQR 2	CONGA 1-2	LBGI 2	HBGI 2
Mean value 2	Correlation	0.33	0.62*	0.34	0.23	−0.39	0.09
	𝑃 value	0.16	<0.01	0.20	0.38	0.13	0.73
MAGE 2	Correlation		0.84*	0.54*	0.54*	0.26	0.69*
	𝑃 value		<0.001	0.03	0.03	0.33	<0.01
SD 2	Correlation			0.66*	0.29	0.27	0.25
	𝑃 value			0.01	0.27	0.31	0.34
IQR 2	Correlation				0.73*	−0.26	0.87*
	𝑃 value				<0.001	0.30	<0.001
CONGA 1-2	Correlation					−0.46*	0.68*
	𝑃 value					0.05	<0.01
LBGI 2	Correlation						−0.40*
	𝑃 value						0.04
HbA1c 3	Correlation	0.52	0.45	0.41	0.52	−0.63*	0.42
	𝑃 value	0.06	0.11	0.15	0.06	0.01	0.14

 *Statistical significance considered for 𝑃<0.05.