Prevalence of Osteoporosis and Its Associated Factors among Older Men with Type 2 Diabetes
Table 3
Effects of T2DM on bone mineral density and bone metabolism.
Control group ()
T2DM group ()
value
Hip
Femoral neck T score
0.006**#
Femoral neck BMD (g/cm2)
0.382#
Trochanter major T score
0.023*#
Trochanter major BMD (g/cm2)
0.021*#
Ward's triangle T score
0.023*#
Ward's triangle BMD (g/cm2)
0.036*#
Femur total T score
0.438#
Femur total BMD (g/cm2)
0.012*#
Lumbar spine
Total spine (L1–L4) T score
0.137#
Total spine (L1–L4) BMD (g/cm2)
0.015*#
Markers of bone resorption
Tartrate-resistant acid phosphatase-5b (U/L)
0.027*
Urinary hydroxyproline/creatinine (g/mol)
0.160
Markers of bone formation
Osteocalcin/bone gla protein (ng/mL)
0.031*
Bone-specific alkaline phosphatase (μg/L)
0.798
Alkaline phosphatase (IU/L)
0.017*
Other markers that may affect bone metabolism
Calcitonin (pg/mL)
0.034*
Parathyroid hormone (pmol/L)
0.042*
25-hydroxy vitamin D3
(nmol/L)
0.052
Insulin-like growth factor I (ng/mL)
0.042*
Serum calcium (mmol/L)
0.048*
Serum phosphorus (mmol/L)
0.031*
Testosterone (nmol/L)
0.073
Symptoms of osteoporosis
Duration of lumbago and back pain (y)
<0.001**
Duration of arthralgia (y)
0.689
Fracture
18 (14.4%)
28 (30.1%)
0.004**
Age of first fracture (y)
0.916
T2DM: type 2 diabetes mellitus; BMD: bone mineral density.
*
; **. Data are expressed as mean ± SD.
#Adjusted for systolic pressure, cigarette smoking, and daily intake of dietary staple foods.
