International Journal of Endocrinology

Clinical Study

A Randomised, Double-Blinded, Placebo-Controlled, Parallel Study of Vitamin D3 Supplementation with Different Schemes Based on Multiples of 25,000 IU Doses

Table 1

Treatment scheme with different intakes of vitamin D according to the 25(OH)D basal level of the subjects.
 Week 0Week 2Week 4Week 8Total
Group 1      
 ≤10 ng/mL      
 Treated group ( ) 75,000 UI 75,000 UI 50,000 UI 50,000 UI 250,000 UI
 Placebo ( )placebo placebo placebo placebo placebo
Group 2      
 >10 ng/mL and ≤20 ng/mL      
 Treated group ( ) 75,000 UI 50,000 UI 25,000 UI 25,000 UI 175,000 UI
 Placebo ( ) placebo placebo placebo placebo placebo
Group 3      
 >20 ng/mL and ≤30 ng/mL      
 Treated group ( ) 50,000 UI 25,000 UI 25,000 UI 25,000 UI 125,000 UI
 Placebo ( ) placebo placebo placebo placebo placebo
Group 4      
 >30 ng/mL and ≤60 ng/mL      
 Treated group ( ) 25,000 UI 25,000 UI 25,000 UI 25,000 UI 100,000 UI
 Placebo ( ) placebo placebo placebo placebo placebo