Clinical Study

Cigarette Smoking Is Associated with Prolongation of the QTc Interval Duration in Patients with Type 2 Diabetes Mellitus

Table 3

Mean values (±SD) of time-domain parameters of HRV during 24-hour, day, and night periods.

Variable (ms)Chronic smokersNonsmokers

SDNN 24 hours114.98 ± 33.05 123.32 ± 39.04 0.348
SDNN day92.64 ± 30.64 97.91 ± 26.15 0.452
SDNN night83.43 ± 27.55 90.41 ± 30.68 0.331
PNN30 24 hours13.79 ± 11.79 13.58 ± 10.99 0.94
PNN30 day 11.70 ± 11.45 10.06 ± 9.3 0.523
PNN30 night17.03 ± 14.71 20 ± 15.81 0.43
RMSSD 24 hours28.41 ± 17.28 28.51 ± 14.18 0.979
RMSSD day26.51 ± 16.07 24.41 ± 12.36 0.553
RMSSD night30.61 ± 22.3 34.01 ± 18.77 0.502
SDANN 5 min 24 hours104.34 ± 31.65 112.5 ± 40.04 0.358
SDANN 5 min day82.04 ± 30.4 86.97 ± 27.95 0.493
SDANN 5 min night62.19 ± 20.94 67.69 ± 31.97 0.407

SDNN: standard deviation of all normal-to-normal RR intervals; PNN30: number of pairs of adjacent NN intervals differing >30 ms in the entire recording divided by the total number of all NN intervals; RMSSD: the square root of the mean of the sum of the squares of differences between adjacent NN intervals; SDANN: 5 min, standard deviation of the averages of NN intervals in all 5-minute segments of the entire recording.