A Double-Blind, Placebo Controlled, Randomized Trial to Assess the Impact of a Monthly Administration of 50,000 IU of Vitamin D3 for 6 Months on Serum Levels of 25-Hydroxyvitamin D in Healthy Young Adults

Table 2

Serum 25(OH)D (ng/mL) levels observed in a young healthy population after 3 and 6 months of supplementation with a monthly dose of 50,000 IU of cholecalciferol or a placebo. The results are expressed as mean ± SD. A P value <0.05 is considered as significant.

	Placebo group	Vitamin D group
Baseline (October)	22.8±8.5	21.2±8.2	NS
After 90 days (February)	14.0±6.9	30.6±8.8	𝑃<0.0001
After 180 days (May)	23.5±8.6	36.0±9.2	𝑃<0.0001
Intragroup comparison
October—February	𝑃<0.0001	𝑃<0.0001
February—May	𝑃<0.0001	𝑃<0.0001
October—May	NS	𝑃<0.0001