Clinical Study
Different Impacts of Metabolic Syndrome Components on Insulin Resistance in Type 2 Diabetes
Table 2
Comparison of characteristics among the groups of nonmetabolic syndrome (NMS), metabolic syndrome A (MSA), and metabolic syndrome B (MSB).
| | Variable | NMS
(components < 2)
| MSA
(components = 2)
| MSB
(components > 2)
| for trend |
| | Basic data | | | | | | HOMA IR* | 3.2 (1.0) | 5.3 (4.0) | 6.1 (3.0) | <0.001 | | Male/female | 29/22 | 19/33 | 17/24 | 0.10 | | Age, year | 60.9 (10.0) | 56.4 (9.4) | 55.8 (10.9) | 0.01 | | FH*, % | 58.8 | 44.2 | 56.1 | 0.29 | | G*, mg/day | 171.0 (39.3) | 175.4 (42.0) | 175.6 (44.6) | 0.59 | | M*, mg/day | 1731.4 (566) | 1763.5 (505) | 1775.6 (727.1) | 0.24 | | BMI*, kg/m2 | 24.2 (2.7) | 27.0 (4.3) | 27.7 (4.9) | <0.001 | | WC*, cm | 82.0 (7.0) | 87.7 (10.9) | 92.0 (10.5) | <0.001 | | HC*, cm | 91.8 (5.9) | 97.5 (10.0) | 99.2 (8.4) | <0.001 | | SBP*, mmHg | 130.1 (13.2) | 135.6 (18.2) | 143.4 (13.3) | <0.001 | | DBP*, mmHg | 75.6 (7.1) | 80.7 (9.9) | 86.5 (8.7) | <0.001 | | MSC, yes % | | | | | | LWC | 20.0 | 71.2 | 80.5 | <0.001 | | HTN | 7.8 | 30.8 | 61.0 | <0.001 | | HTG | 7.8 | 38.8 | 90.2 | <0.001 | | LHDL | 43.1 | 59.6 | 87.8 | <0.001 | | Fasting serum factors | | | | | | Glucose, mg/dL | 185.5 (54.5) | 188.4 (62.9) | 211.1 (51.3) | 0.04 | | HbA1c, % | 9.1 (1.8) | 8.8 (1.5) | 9.7 (1.5) | 0.07 | | Insulin, IU/mL | 7.3 (4.5) | 11.3 (6.8) | 11.9 (6.1) | <0.001 | | Adiponectin, μg/mL | 18.2 (7.3) | 17.8 (8.4) | 14.0 (4.8) | 0.01 | | Fasting lipoprotein | | | | | | Triglyceride, mg/dL | 107.1 (60.8) | 176.7 (190.4) | 297.5 (369.1) | <0.001 | | Cholesterol, mg/dL | 171.8 (38.4) | 171.0 (32.4) | 193.9 (45.5) | 0.01 | | HDL, mg/dL | 44.4 (10.0) | 43.7 (10.2) | 41.3 (6.3) | 0.12 | | LDL, mg/dL | 114.8 (29.4) | 105.0 (32.2) | 115.5 (38.5) | 0.99 |
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NMS: nonmetabolic syndrome; MSA: metabolic syndrome A; MSB: metabolic syndrome B; HOMA IR: HOMA insulin resistance index; FH: family history of type 2 diabetes disease; G: gliclazide; M: metformin; BMI: body mass index; WC: waist circumference; HC: hip circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; LWC: large waist circumference; HTN: high blood pressure; HTG: high triglyceride; LHDL: low HDL-cholesterol; HDL: HDL-cholesterol; LDL: LDL-cholesterol.
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