Clinical Study

Does Q223R Polymorphism of Leptin Receptor Influence on Anthropometric Parameters and Bone Density in Childhood Cancer Survivors?

Table 3

Values of the anthropometric and densitometric parameters in the whole group, according to Q223R LEPR genotype.

Whole groupGGAGAAF P

WHR10.86060.84890.86720.86150.0920.912
Height SDS −0.1974−0.3383−0.22100.16331.4070.260
BMI SDS20.5560.3600.4341.3571.0540.360
BMD total SDS3−0.01320.5292−0.2691−0.13860.8800.423
BMD spine SDS4−0.26100.0383−0.4227−0.26570.8000.457
LEAN SDS50.15020.01800.3396−0.21830.2810.756
FAT SDS64.79436.04884.12504.74710.2650.769
BMC SDS70.32440.60000.19230.26710.4410.647

value between genotype GG and AG.
value between genotype AA and AG.
value between genotype GG and AA.
1WHR: waist to hip ratio.
2BMI SDS: Body Mass Index Standard Deviation Score.
3BMD total SDS: total Bone Mineral Density Standard Deviation Score.
4BMD spine SDS: Bone Mineral Density in the lumbar area Standard Deviation Score.
5LEAN SDS: Lean Mass Standard Deviation Score.
6FAT SDS: Fat Mass Standard Deviation Score.
7BMC SDS: Bone Mineral Content Standard Deviation Score.