Ethynilestradiol 20 mcg plus Levonorgestrel 100 mcg: Clinical Pharmacology

Table 1

Percent (baseline versus end of the study) changes in androgens and SHBG levels over a 3-month period of treatment with EE20/LNG100 (modified from [54]).

Parameter	% change versus baseline	(baseline versus end of treatment)
DHEAS (mcg/mL)	−18.9 ± 40.2	<0.05
Androstenedione (ng/mL)	−36.9 ± 26.7	<0.05
Total testosterone (ng/dL)	−27.0 ± 21.5	<0.05
3-androstanediol glucuronide (ng/mL)	−38.8 ± 36.1	<0.05
SHBG (nmol/L)	106 ± 89	<0.05