Rare Mutations of Peroxisome Proliferator-Activated Receptor Gamma: Frequencies and Relationship with Insulin Resistance and Diabetes Risk in the Mixed Ancestry Population from South Africa

Table 2

Genotype distributions, minor allele frequencies, and unadjusted -values for comparing genotype distribution according to diabetes status and additive allelic effects between diabetes groups.

	No diabetes	Diabetes	-value	Overall
	598	222		820
PPARG (rs3856806)
C/C, (%)	436 (72.9)	172 (77.5)	0.215	608 (74.1)
C/T, (%)	147 (24.5)	48 (21.6)		195 (23.8)
T/T, (%)	15 (2.5)	2 (0.9)		17 (2.1)
T, (%)	177 (14.8)	52 (11.7)	0.128	229 (14.0)
HWE (-value)	0.517	0.747		0.771

HWE: Hardy-Weinberg equilibrium (HWE -values are from exact tests); PPARG: peroxisome proliferator-activated receptor gamma.