Rare Mutations of Peroxisome Proliferator-Activated Receptor Gamma: Frequencies and Relationship with Insulin Resistance and Diabetes Risk in the Mixed Ancestry Population from South Africa

Table 4

Odds ratio and 95% confidence intervals from logistic regression for the prediction of diabetes.

Allele	Covariates	OR (95% CI)
PPARG (rs3856806)T	None	0.76 (0.55 to 1.06)	0.112
	sex, age	0.74 (0.53 to 1.03)	0.082
	sex, age, insulin	0.75 (0.53 to 1.05)	0.098
	sex, age, 2 h insulin	0.56 (0.31 to 0.95)	0.042
	sex, age, HOMA-IR	0.77 (0.53 to 1.10)	0.157
	sex, age, QUICKI	0.75 (0.53 to 1.04)	0.094
	sex, age, FIRI	0.77 (0.53 to 1.10)	0.157
	sex, age, glucose/insulin	0.75 (0.53 to 1.04)	0.092

FIRI: fasting insulin resistance index; HOMA-IR: homeostatic model assessment of insulin resistance; PPARG: peroxisome proliferator-activated receptor; QUICKI: the quantitative insulin-sensitivity check index.