Circulating Sclerostin and Irisin Are Related and Interact with Gender to Influence Adiposity in Adults with Prediabetes

Table 4

(a) Correlation between BMI and age, sclerostin and irisin in male adults with prediabetes () by multivariate analysis. (b) Correlation between BMI and age, sclerostin and irisin in female adults with prediabetes () by multivariate analysis.

(a)

	Model 1		Model 2		Model 3
		value		value		value
Age	−0.55	<0.01	−0.53	<0.01	−0.58	<0.01
Sclerostin			−0.18	0.31	−0.45	<0.05
Irisin					−0.46	<0.05

Model 1: independent variable: age.
Model 2: independent variables: age, sclerostin.
Model 3: independent variables: age, sclerostin, and irisin.

(b)

	Model 1		Model 2		Model 3
		value		value		value
Age	−0.19	0.11	−0.16	0.19	−0.16	0.19
Sclerostin			−0.14	0.24	−0.14	0.26
Irisin					0.001	0.99

Model 1: independent variable: age.
Model 2: independent variables: age, sclerostin.
Model 3: independent variables: age, sclerostin, and irisin.