International Journal of Endocrinology / 2014 / Article / Tab 1

Research Article

Impact of NRAS Mutations on the Diagnosis of Follicular Neoplasm of the Thyroid

Table 1

Clinicopathological features and the NRAS mutation status of 123 follicular neoplasms (FNs).

Patients with a NRAS negative
FN
Patients with a NRAS positive
FN
-value

Average FN size (cm)2.2 ± 1.51.4 ± 0.8<0.001
Age
45 years31 (65%)17 (35%)0.086
 >45 years59 (79%)16 (21%)
Gender
 Female71 (74%)25 (26%)0.710
 Male19 (70%)8 (30%)
Final results of FNs
 Benign52 (83%)11 (17%)0.016
 Malignancy38 (63%)22 (37%)
Final results of coexisting nodules*
 Benign26 (83%)10 (28%)0.080
 Malignancy12 (63%)12 (50%)
Total risk of malignancy53% (47/90)79% (26/33)0.008

Of all 123 patients, 60 had one or more incidental nodules in addition to index nodule with a preoperative diagnosis of FN.