Mild Adrenal Steroidogenic Defects and ACTH-Dependent Aldosterone Secretion in High Blood Pressure: Preliminary Evidence

Table 1

Cosyntropin (1–24 ACTH) test (250 mg, iv at time 0).

	0 min	30 min	60 min
Cortisol [3–23 µg/dL]	16 ± 7 [6–48]	38 ± 11 [20–51]	39 ± 10 [10–51]
17OHP [0–5 ng/mL]	2 ± 1 [1–5]	8 ± 6 [1–39]	8 ± 6 [1–38]
S [0–2 ng/mL]	2 ± 1 [1–8]	6 ± 4 [2–25]	7 ± 4 [2–19]
Renin [1–20 µU/mL]	10 ± 20 [1–149]	11 ± 21 [1–142]	11 ± 18 [1–121]
Aldosterone [10–160 pg/mL]	114 ± 171 [2–859]	221 ± 313 [10–1,628]	334 ± 522 [5–3,656]

Conversion factors are as follows: cortisol µg/dL × 27.59 = cortisol nmol/L; 17OHP ng/mL × 3.026 = 17OHP nmol/L; S ng/mL × 2.887 = S nmol/L; aldosterone pg/mL × 0.002774 = aldosterone nmol/L.