Liraglutide Exerts Antidiabetic Effect via PTP1B and PI3K/Akt2 Signaling Pathway in Skeletal Muscle of KKAy Mice
Figure 4
Effects of liraglutide on PTP1B expression in skeletal muscle. (a) Expression in skeletal muscle of PTP1B mRNA in normal, model, or liraglutide group. Gene expression was measured by real-time PCR. Relative PTP1B mRNA abundance was normalized by β-actin. Data were shown as mean ± SEM, , versus model group, . (b) Expression of PTP1B protein in skeletal muscle from normal, model, or liraglutide group. Lysates from freshly isolated skeletal muscle tissues were measured for PTP1B expression by Western blot analysis. Results were shown as mean ± SEM, , versus model group, .
