Clinical Study

Better Understanding in the Differentiation of Thyroid Follicular Adenoma, Follicular Carcinoma, and Follicular Variant of Papillary Carcinoma: A Retrospective Study

Table 4

Diagnostic performances of USFNA and intraoperative frozen section.

(%)FNA*FNAFS

Sensitivity87.8 (65/74) 84.2 (48/57)80.0 (24/30)
Specificity29.0 (36/124)52.2 (36/69)96.3 (77/80)
PPV42.5 (65/153)59.3 (48/81)88.9 (24/27)
NPV80.0 (36/45)80.0 (36/45)92.8 (77/83)
Accuracy51.0 (101/198)66.7 (84/126)91.8 (101/110)

FNA: fine needle aspiration; FS: frozen section; PPV: positive predictive value; NPV: negative predictive value.
Note: raw data are in parenthesis.
*Inadequate cytology results excluded, indeterminate, suspicious for malignancy and malignant cytology results considered positive.
Inadequate and indeterminate cytology results excluded.
46 nodules excluded due to deferred results on FS.