International Journal of Endocrinology / 2014 / Article / Tab 2

Review Article

Benign Prostatic Hyperplasia: A New Metabolic Disease of the Aging Male and Its Correlation with Sexual Dysfunctions

Table 2

Characteristics of the studies included in the meta-analysis.

Overall population
StudyAge (years)Duration (weeks) DrugsDosage (mg)Placebo number of ptsPDE5 number of pts

McVary et al., 2007 [113]6012Sildenafil50 (2 weeks); 100155168
McVary et al., 2007 [114]*61.512Tadalafil5 (6 weeks); 20126125
Stief et al., 2008 [115]55.98Vardenafil10110105
Roehrborn et al, 2008 [116]*62.012Tadalafil2.5; 5; 10; 20185701
Porst et al., 2009 [117]*61.912Tadalafil2.5; 5; 10; 20105386
Tamimi et al., 2010 [118]*60.912UK-36900310; 25; 50, 10037246
Porst et al., 2011 [119]64.812Tadalafil5152148
Egerdie et al., 2012 [120]*62.512Tadalafil 2.5; 5200406
Oelke et al., 2012 [121]63.612Tadalafil5 172171
Brock et al., 2013 [122]63.312Tadalafil 5545544
Dmochwski et al., 2013 [123]58.612Tadalafil2010199
Yokoyama et al., 2013 [124]*63.212Tadalafil2.5; 5154306

The effect derived from a ponderated mean at end point on International Prostate Symptom Score and maximum urinary flow rate were analyzed.

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