Research Article
Albuminuria Is Associated with Left Ventricular Hypertrophy in Patients with Early Diabetic Kidney Disease
Table 2
The main clinical and biochemical characteristics of type 2 diabetic patients with early diabetic nephropathy.
| | Characteristics | Microalbuminuria | Macroalbuminuria | value | | () | () |
| | Age (year) | 69.4 ± 11.9 | 67.9 ± 12.7 | 0.556 | | Male, (%) | 48 (57.8) | 19 (61.3) | 0.832 | | Hypertension, (%) | 64 (77.1) | 24 (77.4) | 0.972 | | ACEI/ARB use, (%) | 45 (54.2) | 16 (51.6) | 0.804 | | Smoking (%) | 6 (7.23) | 7 (22.6) | 0.022 | | Duration of diabetes (yr) | 9.0 (2.0–14.0) | 10.0 (4.0–18.0) | 0.270 | | SBP (mmHg) | 134.3 ± 17.4 | 140.2 ± 14.0 | 0.096 | | DBP (mmHg) | 79.8 ± 11.4 | 80.3 ± 11.8 | 0.841 | | BMI (kg/m2) | 23.9 ± 3.9 | 24.7 ± 4.0 | 0.383 | | eGFR (mL/min/1.732) | 87.4 (74.7–109.1) | 88.4 (69.4–100.8) | 0.205 | | Laboratory | | | | | Glucose (mmol/L) | 6.8 (5.9–9.2) | 7.2 (6.0–11.9) | 0.352 | | Insulin (μU/mL) | 11.5 (6.9–17.5) | 11.0 (5.6–18.8) | 0.647 | | HOMA-IR | 3.7 (2.0–6.3) | 3.8 (2.3–7.3) | 0.782 | | HbA1c (mean ± SD, %) | 8.5 ± 2.3 | 9.2 ± 1.9 | 0.046 | | Albumin (g/L) | 39.3 ± 4.5 | 36.0 ± 5.3 | <0.001 | | Uric acid (μmol/L) | 0.326 ± 0.089 | 0.321 ± 0.088 | 0.809 | | Creatinine (μmol/L) | 72.4 ± 16.4 | 77.2 ± 17.1 | 0.174 | | ACR (mg/g) | 91.6 (45.7–175.1) | 927.6 (535.8–1525.5) | <0.001 | | Triglycerides (mmol/L) | 1.6 (1.2–2.3) | 1.4 (1.0–2.2) | 0.462 | | Total cholesterol (mmol/L) | 4.9 (4.2–5.4) | 4.5 (4.0–5.5) | 0.839 | | HDL cholesterol (mmol/L) | 1.0 (0.9–1.2) | 1.0 (0.9–1.3) | 0.878 | | LDL cholesterol (mmol/L) | 2.8 ± 0.8 | 2.8 ± 1.0 | 0.840 |
|
|
ACEI/ARB: angiotensin converting enzyme inhibitor/angiotensin receptor blocker; eGFR: modification of diet in renal disease study, glomerular filtration rate; ACR: albumin-to-creatinine ratio; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure.
|
