Research Article
Association of ATM Gene Polymorphism with PTC Metastasis in Female Patients
Table 4
Distribution of genotype frequency by study groups.
| Genotype | Male | | Female | | Metastasis (+) | Metastasis (−) | Metastasis (+) | Metastasis (−) |
| rs664677 | | | 0.993 | | | 0.088 | CC | 15 (31.3) | 16 (30.2) | | 34 (38.6) | 44 (31.9) | | CT | 24 (50.0) | 27 (50.9) | | 38 (43.2) | 79 (57.2) | | TT | 9 (18.8) | 10 (18.9) | | 16 (18.2) | 15 (10.9) | | rs373759 | | | 0.359 | | | 0.249 | GG | 11 (22.9) | 19 (35.8) | | 35 (39.8) | 53 (38.4) | | GA | 31 (64.6) | 29 (54.7) | | 38 (43.2) | 71 (51.4) | | AA | 6 (12.5) | 5 (9.4) | | 15 (17.0) | 14 (10.1) | | rs4988099 | | | 0.493a | | | 0.406 | AA | 45 (93.8) | 47 (88.7) | | 81 (92.0) | 119 (86.9) | | AG | 3 (6.3) | 6 (11.3) | | 7 (8.0) | 17 (12.4) | | GG | 0 (0.0) | 0 (0.0) | | 0 (0.0) | 1 (0.7) | | rs189037 | | | 0.317 | | | 0.126 | GG | 7 (14.3) | 12 (22.6) | | 32 (36.4) | 36 (26.1) | | GA | 33 (67.3) | 28 (52.8) | | 39 (44.3) | 80 (58.0) | | AA | 9 (18.4) | 13 (24.5) |
| 17 (19.3) | 22 (15.9) |
|
|
|
Fisher’s exact test.
|