Functional Analysis of Thyroid Peroxidase Gene Mutations Detected in Patients with Thyroid Dyshormonogenesis
Figure 3
Western blot showing expression of wild-type and mutated recombinant TPO. (a) Lane 1, wild-type recombinant TPO. Lanes 2–4, recombinant TPO containing (2-Glu 641 Lys, 3-Asp 668 Asn, and 4-Thr 725 Pro) changes. In (b) Western blot showing expression of wild-type and mutated recombinant TPO. Lane 1, wild-type recombinant TPO. Lanes 2–4, recombinant TPO containing (2-Asp 620 Asn, 3-Ser 398 Thr, and 4-Ala 373 Ser) changes.
