Stress Hyperglycemia, Insulin Treatment, and Innate Immune Cells

Table 2

Comparison of intensive and moderate insulin treatment.

	Intensive	Moderate
Target	Blood glucose: 110 mg/dL [1]	Blood glucose: 120–150 mg/dL [33, 59]
Advantages	(1) Improves wound healing in burned patients [54]; (2) Reduces urinary tract infections and sepsis in burned pediatric patients [55]; (3) Reduces morbidity and mortality [1]	(1) Does not induce hypoglycemia [60]; (2) Scarce hyperglycemia episodes [60]; (3) Low glucose variability [60]
Disadvantages	(1) Requires continual and critical monitoring [54]; (2) No overall impact on hospital or ICU length of stay [54]; (3) More episodes of hypoglycemia [58]	No significant impact on mortality and multiorgan failure [60]