Research Article

Prevalence of Amiodarone-Induced Thyrotoxicosis and Associated Risk Factors in Japanese Patients

Table 2

Results of univariate Cox proportional hazards regression analysis.

HR (95% )

Gender0.9650.967 (0.214–4.366)
Age<0.00010.927 (0.891–0.964)
TSH0.4570.814 (0.472–1.402)
Free T30.4761.388 (0.563–3.422)
Free T4 0.9251.137 (0.077–16.802)
Cumulative dosage of AMD0.2011.000 (0.999–1.000)
Cardiac disorders
 Chronic heart failure0.7320.048 (0.000–1651676)
 Low left ventricular function0.2771.834 (0.615–5.463)
 Ischemic heart disease0.8591.107 (0.361–3.389)
Arrhythmia
 NSVT0.6070.671 (0.147–3.071)
 Ventricular fibrillation0.2180.298 (0.095–1.360)
 Atrial fibrillation0.9281.099 (0.140–8.606)
Cardiac medications
-blockern/an/a
-blocker0.2140.274 (0.035–2.115)
 Anti-angiotensin agents0.5340.664 (0.183–2.413)
 Anti-aldosteron agents0.2460.516 (0.169–1.578)
 Diuretics0.8891.083 (0.354–3.3118)
 Antithrombotic agents0.4661.616 (0.444–5.882)
 Vasodilators0.8881.114 (0.247–5.028)
 Calcium channel blocker0.9141.087 (0.241–4.904)
 Antiarrhythmic agents0.47822.97 (0.003–132741)

NSVT: nonsustained ventricular tachycardia.
Confidence interval.
n/a: no assign.