High Risk First Degree Relatives of Type 1 Diabetics: An Association with Increases in CXCR3<sup>+</sup> T Memory Cells Reflecting an Enhanced Activity of Th1 Autoimmune Response

<table>The level of IP-10 in the peripheral blood of first degree relatives (FDRs) at high risk (hr FDRs) and low risk (lr FDRs) for development of type 1 diabetes, patients with recent-onset type 1 diabetes in insulin requiring state (RT1D- IRS), and healthy controls. The level of IP-10 was determined by ELISA and shown in box-plots. Horizontal lines represent the median; the box comprises the 25th and 75th percentiles and the error bars comprise the 10th and 90th percentiles. Outliers are indicated. Comparison among hr FDRs, lr FDRs, patients with RT1D-IRS, and healthy controls (ANOVA test).</table>

International Journal of Endocrinology

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Figure 5

Figure 5: High Risk First Degree Relatives of Type 1 Diabetics: An Association with Increases in CXCR3<sup>+</sup> T Memory Cells Reflecting an Enhanced Activity of Th1 Autoimmune Response 

Figure 5 | High Risk First Degree Relatives of Type 1 Diabetics: An Association with Increases in CXCR3+ T Memory Cells Reflecting an Enhanced Activity of Th1 Autoimmune Response 