Effect of GAS6 and AXL Gene Polymorphisms on Adiposity, Systemic Inflammation, and Insulin Resistance in Adolescents

Table 3

Anthropometric and biochemical data with different AXL rs4802113 genotypes among boys and girls.

	Boys			Girls
	TT	TC	CC	TT	TC	CC
	(n = 123)	(n = 170)	(n = 65)	(n = 108)	(n = 181)	(n = 80)
BMI (kg/m^2)	22.0 ± 3.7	22.6 ± 3.8	21.9 ± 4.7	21.4 ± 3.6	21.1 ± 3.2	21.2 ± 3.0
WC (cm)	79.4 ± 10.3	80.8 ± 10.0	79.0 ± 11.9	75.8 ± 9.0	75.2 ± 7.7	76.1 ± 7.9
hsCRP (mg/L)	0.8 ± 1.2^a	1.0 ± 1.4^a	0.8 ± 1.3^a	0.6 ± 0.8	0.6 ± 0.9	0.6 ± 0.9
TNF-α (pg/mL)	24.8 ± 5.5	26.2 ± 6.5	28.2 ± 10.1	24.0 ± 7.3	25.7 ± 8.3	26.6 ± 8.3
IL-6 (pg/mL)	3.0 ± 2.8	3.4 ± 2.7	3.7 ± 3.5	3.5 ± 3.0	2.9 ± 2.0	3.3 ± 2.9
Glucose (mg/dL)	93.4 ± 6.1	94.3 ± 6.0	93.4 ± 7.1	92.0 ± 6.9	91.0 ± 6.5	91.8 ± 6.2
Insulin (μU/mL)	14.8 ± 8.1	15.6 ± 9.7	14.5 ± 7.9	15.2 ± 7.3	14.1 ± 7.8	14.7 ± 7.4
HOMA-IR	3.4 ± 2.0	3.7 ± 2.3	3.4 ± 2.0	3.5 ± 1.7	3.2 ± 1.9	3.3 ± 1.7

Data are expressed as mean ± SD.
BMI: body mass index; WC: waist circumference; HOMA-IR: homeostasis model assessment of insulin resistance; hsCRP: high-sensitivity C-reactive protein; TNF-α: tumor necrosis factor-α; IL-6: interleukin-6.
^aTT versus TC versus CC, P < 0.05. All comparisons were analyzed using a general linear model after adjusting for age, Tanner stages, smoking status, drinking status, and physical activity.