Clinical Study
Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto’s Thyroiditis
Table 1
Clinical and biochemical characteristics of the groups studied.
| | | Control group | Hashimoto’s thyroiditis | value |
| | Age (years) | 38.5 (25.5–54.0) | 50.0 (33.5–56.5) | ns | | BMI (kg/m2) | 22.1 (20.7–27.1) | 27.2 (23.9–32.1) | 0.02 | | Thyroid volume (mL) | 18.5 (12.5–19.5) | 12.2 (7.9–15.3) |
0.001 | | TSH (U/mL) | 1.13 (0.92–1.37) | 1.48 (1.0–1.86) | ns | | TPOAb (U/mL) | 6.14 (4.91–10.17) | 169.7 (27.23–413.27) | 0.00001 | | TRAb (U/L) | 0.30 (0.30–0.53) | 1.16 (0.82–1.35) | 0.00001 | | TNF- (pg/mL) | 5.27 (4.11–6.44) | 6.14 (5.27–7.62) | 0.01 | | Levothyroxine dose (µg/day) | — | 50.0 (0–88.0) | | | Treatment period (years) | — | 4 (2–8) | |
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Data are shown as medians (interquartile range); differences between groups were tested by Mann-Whitney U test.
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