The Effect of Renal Dysfunction on Circulating Sclerostin Level in Patients with Type 2 Diabetes

Table 3

Multiple regression analysis to identify factors associated with serum sclerostin level.

Variables	Group with CKD-G1/2		Group with CKD-G3~5		Total group
	𝛽	𝑃 value	𝛽	𝑃 value	𝛽	𝑃 value
	𝑅^2=0.586		𝑅^2=0.868		𝑅^2=0.809
Age	0.010	0.958	−0.205	0.035	−0.214	0.004
Male sex	0.506	0.009	0.240	0.004	0.172	0.008
Body mass index	0.224	0.296	−0.196	0.033	−0.135	0.074
HbA1C	−0.257	0.164	−0.065	0.385	−0.026	−0.415
Duration of diabetes	0.003	0.987	−0.042	0.621	−0.069	0.372
Calcium	0.146	0.796	−0.002	0.983	−0.118	0.128
Phosphorus	0.128	0.474	0.066	0.517	0.153	0.059
PTH	−0.279	0.112	−0.193	0.141	0.058	0.577
eGFR	−0.166	0.435	−0.868	<0.001	−0.659	<0.001