Primary Thyroid Disorders in Patients with Endogenous Hypercortisolism: An Observational Study

Table 2

Characteristics of 8 patients with Cushing’s syndrome who had evidence of thyroid autoimmunity during followup.

Patient (sex/age)	Pretreatment antibody profile		TFTs	Thyroid USG	Posttreatment antibody profile		TFTs	Urinary cortisol levels (mcg/24 h)
	Anti-Tg	Anti-TPO			Anti-Tg	Anti-TPO		Before cure	After cure
1 (f/62)	Pos	Pos	Euthyroid	Normal	Pos	Pos	Euthyroid	180	44
2 (f/58)	Pos	Neg	Subclinical hypothyroid	Nodular goiter	Pos	Neg	Euthyroid	152	41
3 (f/33)	Neg	Pos	Euthyroid	Thyroiditis	Neg	Pos	Euthyroid	259	45
4 (f/52)	Neg	Pos	Subclinical hyperthyroid	Thyroiditis	Neg	Neg	Euthyroid	151	57
5 (m/63)	Pos	Pos	Euthyroid	Thyroiditis	Pos	Pos	Euthyroid	130	74
6 (f/45)	Neg	Pos	Euthyroid	Nodular goiter	Neg	Pos	Euthyroid	144	65
7 (f/26)	Neg	Neg	Euthyroid	Nodular goiter	Pos	Neg	Euthyroid	145	53
8 (f/58)	Neg	Neg	Euthyroid	Thyroiditis	Neg	Pos	Euthyroid	210	65

TFTs: thyroid function tests; f: female; m: male; anti-Tg: antithyroglobulin antibody; anti-TPO: antithyroperoxidase antibody; pos: positive; neg: negative.
Data on thyroid function tests (TFTs) and autoantibody panel were evaluated 6 months after curative surgery.