Emerging Targets in Pituitary Adenomas: Role of the CXCL12/CXCR4-R7 System

Figure 1

Overexpression of CXCR4 in human pituitary adenomas as compared to normal human adenohypophysis. Immunohistochemical images of human GH-secreting adenoma showing the marked homogeneous positivity for CXCR4 throughout the tissue as compared to scattered staining evidenced in normal anterior pituitary. Hematoxylin and eosin staining and GH-positivity are also depicted. (Original magnification 40x).

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