Prevalence of Nonclassic Congenital Adrenal Hyperplasia in Turkish Children Presenting with Premature Pubarche, Hirsutism, or Oligomenorrhoea

Table 2

Comparisons of clinical and laboratory findings between patients with nonclassic congenital adrenal hyperplasia and premature pubarche.

	IPP (𝑛=65)	NCAH (𝑛=6)	𝑃 value
Gender (female/male)	61/4	6/0	0,697
Age (year)	7,50 (6,95–8,20)	6,90 (6,60–8,85)	0,400
BMI SDS	0,85±0,99	0,94±1,17	0,827
Height SDS	0,71±1,11	0,91±1,15	0,676
Bone Age SDS	1,12±1,02	2,11±0,43	0,022
T.Testosterone (ng/dL)	9,47 (0,30–20)	20 (4,82–45,50)	0,258
Cortisol0 hour (𝜇g/dL)	13±5,36	11,86±3,14	0,594
Cortisol1 hour (𝜇g/dL)	29,20 (24,30–32,20)	31,70 (29–35)	0,121
17-OHP0 hour (ng/mL)	1,18±1,01	6,33±4,96	0,052
17-OHP1 hour (ng/mL)	3 (2,20–4)	25,30 (9,97–39,32)	<0,001
DHEA-S0 hour (𝜇g/dL)	65,20 (43,70–107)	62,40 (40,77–128,50)	0,960
DHEA-S1 hour (𝜇g/dL)	67,70 (43,45–101)	64,50 (45,70–131,25)	0,848

Data are expressed as means ± standard deviations or medians (Q1–Q3) as appropriate. IPP: idiopathic premature pubarche; NCAH: nonclassic congenital adrenal hyperplasia; BMI SDS: body mass index standard deviation score; 17-OHP: 17-hydroxyprogesterone; DHEA-S: dehydroepiandrosterone sulphate.