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International Journal of Endocrinology
Volume 2014, Article ID 794943, 7 pages
Research Article

Subacute Thyroiditis: Clinical Presentation and Long Term Outcome

1Department of Medicine, College of Medicine, King Saud University, P.O. Box 2925 (38), Riyadh 11461, Saudi Arabia
2Clinical Chemistry Unit, Department of Pathology, College of Medicine, King Saud University, P.O. Box 2925 (30), Riyadh 11461, Saudi Arabia
3Department of Medical Biochemistry, Faculty of Medicine, Ain Shams University, Abbassia, Cairo 11566, Egypt
4National Neuroscience Institute, King Fahad Medical City, Riyadh 11525, Saudi Arabia
5Neurology Department, King Faisal Specialist Hospital & Research Center, Riyadh 11211, Saudi Arabia

Received 1 December 2013; Revised 17 February 2014; Accepted 19 February 2014; Published 3 April 2014

Academic Editor: Ajai Kumar Srivastav

Copyright © 2014 Assim A. Alfadda et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Few studies have been reported from the Kingdom of Saudi Arabia (SA) to describe the clinical presentation and long term outcomes of subacute thyroiditis (SAT). Our aim was to review the demographic, anthropometric, clinical presentation, laboratory results, treatment, and disease outcome in Riyadh region and to compare those with results from different regions of the Kingdom and different parts of the world. We reviewed the medical files of patients who underwent thyroid uptake scan during an 8-year period in King Khalid University Hospital. Only 25 patients had confirmed diagnosis of thyroiditis. Age and gender distribution were similar to other studies. Most patients presented with palpitation, goiter, and weight change. Elevated thyroid hormones, suppressed thyroid-stimulating hormone, and elevated ESR were reported. Among those, 7 cases of SAT were recorded. β-Blockers were prescribed to 57% and nonsteroidal anti-inflammatory drugs to 29% of SAT. Long follow-up demonstrated that 85.7% of SAT cases recovered, while 14.3% developed permanent hypothyroidism. In conclusion, SAT is uncommon in the central region of SA. Compared to the western region, corticosteroid is not commonly prescribed, and permanent hypothyroidism is not uncommon. A nation-wide epidemiological study to explain these interprovincial differences is warranted.