Baicalein Protects against Type 2 Diabetes via Promoting Islet β-Cell Function in Obese Diabetic Mice

Figure 1

Baicalein supplementation had no effects on food consumption, BW, body composition, or the plasma lipid profile in HF diet-induced obese mice. C57BL/6 male, retired breeder (8 mo) mice were used for this study. Food intake was recorded every 2 or 3 days and cumulative weekly food consumption was calculated (a). BW was monitored every wk (b). Body composition during the final week of the trial was measured with fat tissue mass (c) and lean mass (d) expressed as a percentage of the BW. At the end of the 8th wk of the experiment, fasting plasma total cholesterol (e), HDL-cholesterol (f), and triglycerides (g) were measured. Values represent mean ± SE (𝑛=10/group). ^∗𝑃<0.05 versus SD group. BW: body weight, SD: standard diet, HF: high-fat diet, and HF + B: HF + 0.5 g baicalein/kg diet.

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