Research Article

Baicalein Protects against Type 2 Diabetes via Promoting Islet β-Cell Function in Obese Diabetic Mice

Figure 5

Baicalein supplementation improved pancreatic -cell mass and reduced apoptosis. Pancreatic sections from mice given SD, HF, HF, and STZ administration (HF + STZ) and HF + STZ supplemented with baicalein (B, 0.5 g/kg diet) were fluorescently stained with insulin (a) or double stained with activated caspase-3 (red) and insulin (blue) (b). The -cell mass was determined as described in the Methods section (c). Data are shown as means ± SE ( mice/group). versus SD group, versus HF + STZ group.
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(a)
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(b)
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(c)