Effects of Maternal Hypoxia during Pregnancy on Bone Development in Offspring: A Guinea Pig Model

Figure 5

Effects of MH on numbers of adipocytes in the lower secondary spongiosa of tibial bone. (a) Bone marrow in fetal guinea pigs does not contain adipocytes (a section from a control fetal guinea pig). Bone marrow showing presence of adipocytes in a day 120 postnatal guinea pig from a control (b) and a hypoxic mother (c). (d) Bone marrow adipocytes/mm² marrow area from control and hypoxia-treated mothers. 𝑛=5. Scale bar in (a) = 500 μm and applies to (b) and (c).

(a)

(b)

(c)

(d)