Research Article
Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease
Table 3
Diagnostic index of individual CT features for detecting diffuse thyroid disease in 209 patients.
| CT features | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) |
| Degree of attenuation | | | | | | Iso- | 18/52 (34.6) | 27/157 (17.2) | 18/148 (12.2) | 27/61 (44.3) | 45/209 (21.5) | Low | 34/52 (65.4) | 130/157 (82.8) | 34/61 (55.7) | 130/148 (87.8) | 164/209 (78.5) | Pattern of attenuation | | | | | | Homogeneous | 17/52 (32.7) | 15/157 (9.6) | 17/159 (10.7) | 15/50 (30) | 32/209 (15.3) | Inhomogeneous | 35/52 (67.3) | 143/157 (91.1) | 35/49 (71.4) | 143/160 (89.4) | 178/209 (85.2) | Heterogeneous | 0/52 (0) | 156/157 (99.4) | 0/1 (0) | 156/208 (75) | 156/209 (74.6) | Size of thyroid gland | | | | | | Normal | 38/52 (73.1) | 23/157 (14.7) | 38/172 (22.1) | 23/37 (62.2) | 61/209 (29.2) | Increased | 14/52 (26.9) | 135/157 (86.0) | 14/36 (38.9) | 135/173 (78.0) | 149/209 (71.3) | Decreased | 0/52 (0) | 156/157 (99.4) | 0/1 (0) | 156/208 (75) | 156/209 (74.6) | Margin of thyroid gland | | | | | | smooth | 40/52 (76.9) | 4/157 (2.5) | 40/193 (20.7) | 4/16 (25) | 44/209 (21.1) | Lobulated | 12/52 (23.1) | 153/157 (97.5) | 12/16 (75) | 153/193 (79.3) | 165/209 (78.9) | Pattern of enhancement | | | | | | Homogeneous | 22/52 (42.3) | 5/157 (3.2) | 22/174 (12.6) | 5/35 (14.3) | 27/209 (12.9) | Inhomogeneous | 30/52 (57.7) | 152/157 (96.8) | 30/35 (85.7) | 152/174 (87.4) | 182/209 (87.1) |
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Data in parentheses are percentage of each item. PPV: positive predictive value; NPV: negative predictive value.
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