Research Article

Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease

Table 3

Diagnostic index of individual CT features for detecting diffuse thyroid disease in 209 patients.

CT featuresSensitivity (%)Specificity (%)PPV (%)NPV (%)Accuracy (%)

Degree of attenuation
 Iso-18/52 (34.6)27/157 (17.2)18/148 (12.2)27/61 (44.3)45/209 (21.5)
 Low34/52 (65.4)130/157 (82.8)34/61 (55.7)130/148 (87.8)164/209 (78.5)
Pattern of attenuation
 Homogeneous17/52 (32.7)15/157 (9.6)17/159 (10.7)15/50 (30)32/209 (15.3)
 Inhomogeneous35/52 (67.3)143/157 (91.1)35/49 (71.4)143/160 (89.4)178/209 (85.2)
 Heterogeneous0/52 (0)156/157 (99.4)0/1 (0)156/208 (75)156/209 (74.6)
Size of thyroid gland
 Normal38/52 (73.1)23/157 (14.7)38/172 (22.1)23/37 (62.2)61/209 (29.2)
 Increased14/52 (26.9)135/157 (86.0)14/36 (38.9)135/173 (78.0)149/209 (71.3)
 Decreased0/52 (0)156/157 (99.4)0/1 (0)156/208 (75)156/209 (74.6)
Margin of thyroid gland
 smooth40/52 (76.9)4/157 (2.5)40/193 (20.7)4/16 (25)44/209 (21.1)
 Lobulated12/52 (23.1)153/157 (97.5)12/16 (75)153/193 (79.3)165/209 (78.9)
Pattern of enhancement
 Homogeneous22/52 (42.3)5/157 (3.2)22/174 (12.6)5/35 (14.3)27/209 (12.9)
 Inhomogeneous30/52 (57.7)152/157 (96.8)30/35 (85.7)152/174 (87.4)182/209 (87.1)

Data in parentheses are percentage of each item. PPV: positive predictive value; NPV: negative predictive value.