Clinical Study

Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules

Table 1

Patients’ characteristics at baseline before either RFA or surgery.

CharacteristicsRFA ( )Surgery ( ) value

Age (years)58.3 ± 3.654.9 ± 3.4n.s.
Sex (M/F)12/2517/57n.s.
Nodule maximum (mm)35.7 ± 2.538.8 ± 3.2n.s.
Nodule volume (mL)12.4 ± 2.512.8 ± 2.1n.s.
Solid nodules (Y/N)28/943/31n.s.
Vascularity2.1 ± 0.12.1 ± 0.2n.s.
Macrocalcifications (Y/N)8/2919/55n.s.
Patients with symptoms (Y/N)13/2443/31*0.03
Hyperthyroidism (Y/N)12/2520/54n.s.
TSH (microU/mL)1.2 ± 0.2 1.3 ± 1.9n.s.
Calcitonin (pg/mL)1.8 ± 0.32.8 ± 0.5n.s.
Anti-TPO and/or anti-TG Ab (Y/N)3/347/67 n.s.

Results are expressed as mean ± SEM. Anti-TPO Ab, anti-thyroperoxidase antibodies; anti-TG Ab, anti-thyroglobulin antibodies; n.s., nonsignificant; RFA, radiofrequency ablation; TSH, thyroid-stimulating hormone; Y/N, yes/no. Solid nodules had less than 50% of cystic component.