Repeat FNA Significantly Lowers Number of False Negative Results in Patients with Benign Nodular Thyroid Disease and Features of Chronic Thyroiditis
Table 1
Cytological diagnoses in repeat FNAs in patients of BL-CT and BL-nCT groups.
BL-CT group
BL-nCT group
Number of patients
787
5147
Mean age ± SD (years)
54.7 ± 14.4
57.2 ± 16.3
Number/% males in group
28/3.6
544/10.6
Mean thyroid volume ± SD (cm3) assessed by US examination
21.3 ± 15.1
24.3 ± 14.4
Mean nodule volume ± SD (cm3) assessed by US examination
2.3 ± 12.7
4.2 ± 9.9
Category of cytological diagnosis in repeat FNAB
Number/%
Number/%
ND
59/7.5
299/5.8
NS
BL
696/88.4
4687/91.1
NS
FLUS
7/0.9
62/1.2
NS
FN/SFN
16/2.0
64/1.2
NS
SM
3/0.4
17/0.3
NS
MN
6/0.8
18/0.3
NS
Cytological indication for surgical treatment in control FNA/% of all cases
25/3.2
99/1.9
Diagnosis or suspicion of PTC in control FNA/% of SM and MN results
8/88.9
26/74.3
NS
ND: nondiagnostic FNA, BL-CT: benign lesions with features of chronic thyroiditis, BL-nCT: benign lesion without features of chronic thyroiditis, FLUS: follicular lesions of undetermined significance, FN: follicular neoplasm/tumour, SFN: suspicious for follicular neoplasm, SM: suspicious for malignancy, MN: malignant neoplasm, PTC: papillary carcinoma.