Research Article

Genetic Variations in the Kir6.2 Subunit (KCNJ11) of Pancreatic ATP-Sensitive Potassium Channel Gene Are Associated with Insulin Response to Glucose Loading and Early Onset of Type 2 Diabetes in Childhood and Adolescence in Taiwan

Table 2

Genotypic distribution of E23K polymorphism of the Kir6.2 between normal control and type 2 diabetes subjects.

Non-DM ()DM () value*Odds ratio95% confidence interval

Genotype*
 EE, (%)24 (34.8%)6 (15.8%)
 EK/KK, (%)45 (65.2%)32 (84.2%)0.0442.841.04–7.75
Allele
 E-allele, (%)81 (58.7%)38 (50.0%)
 K-allele, (%)57 (41.3%)38 (50.0%)0.2511.420.81–2.50

Chi-squared test.