Correlations of Vascular Architecture and Angiogenesis with Pituitary Adenoma Histotype

Figure 2

Determination of VEGF mRNA expression and immunohistochemistry. (a) VEGF mRNA expression and corresponding VEGF immunohistochemistry results (positive and negative) and vessel density (number/0.13 mm², , ). (b) The VEGF₁₆₅/-actin ratio was significantly higher in VEGF-positive group than the VEGF-negative group (). (c) The VEGF₁₂₁/-actin ratio was significantly higher in the VEGF-positive group than the VEGF-negative group (). (d) The correlation between VEGF₁₆₅/-actin ratio and vessel density was not significant (). (e) Correlation between VEGF₁₂₁/-actin ratio and vessel density is not significant (). (f) Correlation between VEGF₁₆₅/-actin ratio and vessel diameter is not significant (). (g) Correlation between VEGF₁₂₁/-actin ratio and vessel density is not significant ().

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