17β Estradiol Modulates Perfusion Pressure and Expression of 5-LOX and CYP450 4A in the Isolated Kidney of Metabolic Syndrome Female Rats

Figure 2

Arachidonic acid effect on perfusion pressure in isolated kidney from experimental groups. Kidneys were perfused with 4 μg of AA in the absence or the presence of inhibitors. AA 4 μg, AA 4 μg plus 10 μmo/L Baicalein, AA 4 μg plus 5 μmol/L Miconazole, and 1 AA 4 μg plus 10 μmo/L Indomethacin. C: control, MS: metabolic syndrome, MSovx: metabolic syndrome ovariectomized, and MSovx + E₂: metabolic syndrome ovariectomized plus estradiol. Data are means ± SE; in each group. MS versus MSovx .