Switching from Twice-Daily Basal Insulin Injections to Once-Daily Insulin Degludec Injection for Basal-Bolus Insulin Regimen in Japanese Patients with Type 1 Diabetes: A Pilot Study
Table 3
Comparisons of glucose fluctuation and the frequency of hypoglycemic episodes over 4 days measured by iPro2 before and after switching from basal insulin to insulin degludec.
Before
4 weeks
Daytime (6:00–23:59)
Average blood glucose (mg/dL)
184.1 ± 45.8
189.6 ± 52.7
0.58
SD (mg/dL)
68.4 ± 14.5
66.5 ± 17.1
0.64
MODD (mg/dL)
72.1 ± 16.0
74.0 ± 23.0
0.68
Frequency of hypoglycemia (%)
6.1 ± 8.0
6.5 ± 9.7
0.87
Nighttime (0:00–5:59)
Average blood glucose (mg/dL)
156.5 ± 63.7
174.6 ± 58.5
0.05
SD (mg/dL)
22.6 ± 10.9
24.8 ± 10.7
0.25
MODD (mg/dL)
66.2 ± 30.7
83.3 ± 36.9
0.08
Frequency of hypoglycemia (%)
14.4 ± 17.0
11.1 ± 15.0
0.45
Data are mean ± SD. CGM data were analyzed for 4 consecutive days.
