Treated Autoimmune Thyroid Disease Is Associated with a Decreased Quality of Life among Young Persons with Type 1 Diabetes
Table 1
Characteristics of respondents.
All patients
Thyroid disease status
Celiac disease status
No thyroid disease
Autoantibodies + normal TSH (T1D + AB, untreated)
Autoantibodies + high TSH upon diagnosis (T1D + AITD, treated)
No celiac disease
Celiac disease (T1D + CD)
248
143 (57.6%)
65 (26.2%)
40 (16.1%)
222 (89.5%)
26 (10.5%)
Females (, %)
118 (47.6%)
63 (44.0%)
27 (41.5%)
28 (70.0%)a
104 (46.8%)
14 (53.8%)
Age (years)
13.7 (11.6–16.6)
13.3 (11.3–16.0)
14.0 (10.9–16.7)
15.2 (13.2–17.2)b
13.4 (11.7–13.9)
13.4 (11.7–13.9)
T1D treatment
Insulin pen
156
90
39
27
142
14
Insulin pump
96 (38.7%)
53 (37.0%)
26 (40.0%)
13 (32.5%)
80 (36.0%)
12 (46.1%)
HbA1c (mmol/mol IFCC)
68 (60–77)
67 (60–75)
66 (60–76)
75 (63–82)c
68 (60–77)
72 (60–83)
Diabetes duration (years)
6.3 (3.0–9.3)
5.8 (2.8–9.3)
5.7 (2.8–8.8)
7.8 (5.2–10.6)
5.9 (2.8–9.3)
7.6 (4.9–9.1)
Data are described as median (interquartile range) or (%).
= 0.0065 as compared to subjects with no thyroid disease; = 0.0017 as compared to subjects with no thyroid disease; = 0.044 as compared to subjects with no thyroid disease.
