Review Article
The Involvement of GAS6 Signaling in the Development of Obesity and Associated Inflammation
Table 2
GAS6 signaling molecules and the development of obesity in clinical studies.
| Model | Comparison | Age | GAS6 (plasma, ng/mL) | Axl (plasma, ng/mL) | BMI (kg/m2) | References |
| T2DM | Normal versus T2DM | versus | versus | | versus |
Lee et al., 2012 [26], Hung et al., 2010 [17] |
| T2DM | Normal versus T2DM | versus | versus | | |
Lee et al., 2014 [29] |
| Human | Male versus female | versus | versus | | versus | Kuo et al., 2014 [19] |
| Female | Pre- versus postmenopausal | versus | versus | | versus | Hung et al., 2014 [20] |
| Adolescents | Lean versus obesity | versus | versus | versus | versus | Hsiao et al., 2013 [11] |
| Boys with GAS6 rs8191974 genotype | GG versus AA | | versus | | versus | Hsiao et al., 2014 [12] |
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. T2DM: type 2 diabetes mellitus patients.
|