Sodium Valproate Enhances the Urethane-Induced Lung Adenomas and Suppresses Malignization of Adenomas in Ovariectomized Female Mice

Table 1

Incidence of lung tumors in female BALB/c mice of the study groups.

Groups of mice	Initial mice number ()	Mice data after 6 months
			Body weight m ± SD (g)	Mice with tumors (%)
Intact control	15	15	24.3 ± 1.1	0
Ovariectomized control	15	12	24.0 ± 3.6	0
Intact U-treated	15	10	21.4 ± 2.9	100
Ovariectomized U-treated	15	12	22.8 ± 3.9	100
Intact U-NaVP-treated	15	13	20.4 ± 3.7	100
Ovariectomized U-NaVP-treated	15	14	21.9 ± 3.7	100
Intact NaVP-treated	15	15	20.0 ± 3.2	0
Ovariectomized NaVP-treated	15	15	25.4 ± 2.4	0