Research Article

High Levels of Perfluorooctane Sulfonate in Children at the Onset of Diabetes

Table 4

Results of multivariate linear regression analysis on PFOS and PFOA levels in serum.

PFOSPFOA
All population ( 44)T1DM ( 25)Controls ( 19)All population ( 44)T1DM ( 25)Controls ( 19)

SE1.211.350.150.080.090.06
()0.43 (0.18)0.63 (0.40)0.64 (0.41)0.35 (0.12)0.50 (0.26)0.63 (0.39)
value0.2690.1170.3320.5490.4350.380

Intercept
 Coeff.1.012.840.410.710.850.42
  SE1.972.580.500.140.180.21
value0.6130.2850.430<0.001<0.0010.069

Age
 Coeff.0.130.430.17−0.24−0.07−0.20
  SE0.160.190.250.160.210.25
value0.4040.0350.5230.1430.7510.449

BMI -score
 Coeff.−0.11−0.21−0.010.02−0.230.43
  SE0.170.200.290.170.220.29
value0.5070.3060.9680.8890.3220.172

TC
 Coeff.0.820.020.44−0.20−0.860.12
  SE0.380.600.700.390.670.72
value0.0400.9720.5440.6140.2190.864

HDL-C
 Coeff.−0.34−0.14−0.70−0.100.09−0.20
  SE0.240.380.390.250.420.39
value0.1720.7190.0970.6920.8340.618

TG
 Coeff.−0.44−0.470.47−0.14−0.070.09
  SE0.190.270.290.200.300.30
value0.0290.0990.1410.4960.8040.753

LDL-C
 Coeff.−0.74−0.04−0.240.220.750.19
  SE0.370.610.620.380.680.63
value0.0540.9460.7060.5590.2880.765

-BMI: -score body mass index; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol; PFOA: perfluorooctanoic acid; PFOS: perfluorooctane sulfonate; SE: standard error; TC: total cholesterol; TG: triglycerides; T1DM: type 1 diabetes.