Research Article
High Levels of Perfluorooctane Sulfonate in Children at the Onset of Diabetes
Table 4
Results of multivariate linear regression analysis on PFOS and PFOA levels in serum.
| | PFOS | PFOA | All population ( 44) | T1DM ( 25) | Controls ( 19) | All population ( 44) | T1DM ( 25) | Controls ( 19) |
| SE | 1.21 | 1.35 | 0.15 | 0.08 | 0.09 | 0.06 | () | 0.43 (0.18) | 0.63 (0.40) | 0.64 (0.41) | 0.35 (0.12) | 0.50 (0.26) | 0.63 (0.39) | value | 0.269 | 0.117 | 0.332 | 0.549 | 0.435 | 0.380 |
| Intercept | | | | | | | Coeff. | 1.01 | 2.84 | 0.41 | 0.71 | 0.85 | 0.42 | SE | 1.97 | 2.58 | 0.50 | 0.14 | 0.18 | 0.21 | value | 0.613 | 0.285 | 0.430 | <0.001 | <0.001 | 0.069 |
| Age | | | | | | | Coeff. | 0.13 | 0.43 | 0.17 | −0.24 | −0.07 | −0.20 | SE | 0.16 | 0.19 | 0.25 | 0.16 | 0.21 | 0.25 | value | 0.404 | 0.035 | 0.523 | 0.143 | 0.751 | 0.449 |
| BMI -score | | | | | | | Coeff. | −0.11 | −0.21 | −0.01 | 0.02 | −0.23 | 0.43 | SE | 0.17 | 0.20 | 0.29 | 0.17 | 0.22 | 0.29 | value | 0.507 | 0.306 | 0.968 | 0.889 | 0.322 | 0.172 |
| TC | | | | | | | Coeff. | 0.82 | 0.02 | 0.44 | −0.20 | −0.86 | 0.12 | SE | 0.38 | 0.60 | 0.70 | 0.39 | 0.67 | 0.72 | value | 0.040 | 0.972 | 0.544 | 0.614 | 0.219 | 0.864 |
| HDL-C | | | | | | | Coeff. | −0.34 | −0.14 | −0.70 | −0.10 | 0.09 | −0.20 | SE | 0.24 | 0.38 | 0.39 | 0.25 | 0.42 | 0.39 | value | 0.172 | 0.719 | 0.097 | 0.692 | 0.834 | 0.618 |
| TG | | | | | | | Coeff. | −0.44 | −0.47 | 0.47 | −0.14 | −0.07 | 0.09 | SE | 0.19 | 0.27 | 0.29 | 0.20 | 0.30 | 0.30 | value | 0.029 | 0.099 | 0.141 | 0.496 | 0.804 | 0.753 |
| LDL-C | | | | | | | Coeff. | −0.74 | −0.04 | −0.24 | 0.22 | 0.75 | 0.19 | SE | 0.37 | 0.61 | 0.62 | 0.38 | 0.68 | 0.63 | value | 0.054 | 0.946 | 0.706 | 0.559 | 0.288 | 0.765 |
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-BMI: -score body mass index; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol; PFOA: perfluorooctanoic acid; PFOS: perfluorooctane sulfonate; SE: standard error; TC: total cholesterol; TG: triglycerides; T1DM: type 1 diabetes.
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