Ghrelin’s Effects on Proinflammatory Cytokine Mediated Apoptosis and Their Impact on β-Cell Functionality

Figure 4

Ghrelin and cytokines’ effects on ER stress response markers. Real-time quantitative PCR reaction was performed to measure gene levels of EIF2AK3 (a), EIF2A (b), HSPA4 (c), and HSPA5 (d) in cytokines treated cultures alone or in presence of ghrelin. Results are presented as mean ± SEM of mRNA expression indicated as arbitrary units. Values were obtained from 4 independent experiments. between groups. C, control; CTK, cytokines; GHR, ghrelin; CTK + GHR, cytokines + ghrelin.

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