Correlation between B-Type Natriuretic Peptide and Functional/Cognitive Parameters in Discharged Congestive Heart Failure Patients

Table 1

Main demographic, clinical, and laboratory data.

Clinical features	Patients ()	Range
Age (years)	70.8 ± 10.3	30–92
Female	352 (37%)
Mean ejection fraction (%); (i) Ejection fraction ≤50%	46.9 ± 14.4; 548 (57.6%)	10–89
Heart failure severity (NYHA class at admission)
(i) NYHA II	388 (40.8%)
(ii) NYHA III	326 (34.3%)
(iii) NYHA IV	90 (9.5%)
BNP level at admission (pg/mL)	549.1 ± 898.2	4–17860
Creatinine plasma level (mg/dL)	1.17 ± 0.6	0.4–6.3
Creatinine clearance (according to Cockroft-Gault equation) (mL/min)	62.3 ± 25.4	15–129
Sodium serum level (mg/dL)	139.6 ± 7.3	120–152
Body mass index (BMI) ()	25.5 ± 5.4	15–39
Heart failure etiology
(i) Coronary artery disease	445 (46.8%)
(a) Previous by-pass graft surgery	251 (26.4%)
(b) Previous percutaneous revascularization	96 (10.1%)
(ii) Valvular cardiomyopathy	258 (43.7%)
Atrial fibrillation	199 (21%)
AICD	82 (8.6%)
6-minute walking test (meters)	310.7 ± 93.0	50–570
Barthel index	86.3 ± 23.4	0–100
Score on MMSE	27.3 ± 3.2	10–30
GDS 15 items	6.4 ± 3.5	0–15

NYHA: New York Heart Association; BNP: B-type natriuretic peptide; AICD: automatic implantable cardioverter defibrillator; MMSE: Mini Mental State Examination; GDS: Geriatric Depression Scale.