Clinical Study

Low Growth Hormone Levels in Short-Stature Children with Pituitary Hyperplasia Secondary to Primary Hypothyroidism

Figure 1

Changes in pituitary hyperplasia and low GH levels in short-stature children with PPH before and after L-T4 therapy. In eight children (solid lines), pituitary hyperplasia and low GH levels returned to normal after 3 months of L-T4 therapy. In three children (patients 4, 5, and 6) (dotted lines), pituitary hyperplasia returned to normal after 6 months of L-T4 therapy. GH levels returned to normal in patient 4 and were still low in patients 5 and 6.
(a)
(b)