Table of Contents Author Guidelines Submit a Manuscript
International Journal of Endocrinology
Volume 2015 (2015), Article ID 348757, 6 pages
http://dx.doi.org/10.1155/2015/348757
Research Article

Elevated Systemic Neutrophil Count Is Associated with Diabetic Macroalbuminuria among Elderly Chinese

Department of Endocrinology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai 200240, China

Received 29 August 2015; Revised 19 October 2015; Accepted 8 November 2015

Academic Editor: Marco Bugliani

Copyright © 2015 Min Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. F. Navarro-González, C. Mora, M. Muros, J. García, J. Donate, and V. Cazaña, “Relationship between inflammation and microalbuminuria in prehypertension,” Journal of Human Hypertension, vol. 27, no. 2, pp. 119–125, 2013. View at Publisher · View at Google Scholar · View at Scopus
  2. P. Ruggenenti, P. Cravedi, and G. Remuzzi, “Mechanisms and treatment of CKD,” Journal of the American Society of Nephrology, vol. 23, no. 12, pp. 1917–1928, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. L. M. Ruilope and G. L. Bakris, “Renal function and target organ damage in hypertension,” European Heart Journal, vol. 32, no. 13, pp. 1599–1604, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. X. Wang, W. Bao, J. Liu et al., “Inflammatory markers and risk of type 2 diabetes: a systematic review and meta-analysis,” Diabetes Care, vol. 36, no. 1, pp. 166–175, 2013. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Festa, R. D’Agostino, G. Howard, L. Mykkanen, R. P. Tracy, and S. M. Haffner, “Inflammation and microalbuminuria in nondiabetic and type 2 diabetic subjects: the Insulin Resistance Atherosclerosis study,” Kidney International, vol. 58, no. 4, pp. 1703–1710, 2000. View at Publisher · View at Google Scholar · View at Scopus
  6. V. Perkovic, C. Verdon, T. Ninomiya et al., “The relationship between proteinuria and coronary risk: a systematic review and meta-analysis,” PLoS Medicine, vol. 5, no. 10, article e207, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. B. Feldt-Rasmussen, “Microalbuminuria, endothelial dysfunction and cardiovascular risk,” Diabetes and Metabolism, vol. 26, supplement 4, pp. 64–66, 2000. View at Google Scholar · View at Scopus
  8. D. Versari, E. Daghini, A. Virdis, L. Ghiadoni, and S. Taddei, “Endothelial dysfunction as a target for prevention of cardiovascular disease,” Diabetes Care, vol. 32, supplement 2, pp. S314–S321, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. F. Gobal, A. Deshmukh, S. Shah, and J. L. Mehta, “Triad of metabolic syndrome, chronic kidney disease, and coronary heart disease with a focus on microalbuminuria: death by overeating,” Journal of the American College of Cardiology, vol. 57, no. 23, pp. 2303–2308, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. H.-K. Kuo, S. Al Snih, Y.-F. Kuo, and M. A. Raji, “Cross-sectional associations of albuminuria and C-reactive protein with functional disability in older adults with diabetes,” Diabetes Care, vol. 34, no. 3, pp. 710–717, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. T. T. Nguyen and T. Y. Wong, “Retinal vascular manifestations of metabolic disorders,” Trends in Endocrinology and Metabolism, vol. 17, no. 7, pp. 262–268, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. J. M. Forbes and M. E. Cooper, “Mechanisms of diabetic complications,” Physiological Reviews, vol. 93, no. 1, pp. 137–188, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. B. C. Callaghan, J. Hur, and E. L. Feldman, “Diabetic neuropathy: one disease or two?” Current Opinion in Neurology, vol. 25, no. 5, pp. 536–541, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. J. F. Navarro, C. Mora, M. Gómez, M. Muros, C. López-Aguilar, and J. García, “Influence of renal involvement on peripheral blood mononuclear cell expression behaviour of tumour necrosis factor-α and interleukin-6 in type 2 diabetic patients,” Nephrology Dialysis Transplantation, vol. 23, no. 3, pp. 919–926, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. L. Jiang, W. Huang, Y. Liang et al., “Metabolic syndrome, C-reactive protein and microalbuminuria in a rural Chinese population: a cross-sectional study,” BMC Nephrology, vol. 14, article 118, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. S. J. Woo, S. J. Ahn, J. Ahn, K. H. Park, and K. Lee, “Elevated systemic neutrophil count in diabetic retinopathy and diabetes: a hospital-based cross-sectional study of 30,793 Korean subjects,” Investigative Ophthalmology and Visual Science, vol. 52, no. 10, pp. 7697–7703, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. W. W. Chance, C. Rhee, C. Yilmaz et al., “Diminished alveolar microvascular reserves in type 2 diabetes reflect systemic microangiopathy,” Diabetes Care, vol. 31, no. 8, pp. 1596–1601, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. S. Hadjadj, R. Aubert, F. Fumeron et al., “Increased plasma adiponectin concentrations are associated with microangiopathy in type 1 diabetic subjects,” Diabetologia, vol. 48, no. 6, pp. 1088–1092, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, “Report of the expert committee on the diagnosis and classification of diabetes mellitus,” Diabetes Care, vol. 20, no. 7, pp. 1183–1197, 1997. View at Publisher · View at Google Scholar
  20. S. Ayilavarapu, A. Kantarci, G. Fredman et al., “Diabetes-induced oxidative stress is mediated by Ca2+-independent phospholipase A2 in neutrophils,” Journal of Immunology, vol. 184, no. 3, pp. 1507–1515, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. M. F. Lopes-Virella, N. L. Baker, K. J. Hunt, P. A. Cleary, R. Klein, and G. Virella, “Baseline markers of inflammation are associated with progression to macroalbuminuria in type 1 diabetic subjects,” Diabetes Care, vol. 36, no. 8, pp. 2317–2323, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. D. Cai, “One step from prediabetes to diabetes: hypothalamic inflammation?” Endocrinology, vol. 153, no. 3, pp. 1010–1013, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Y. Donath, É. Dalmas, N. S. Sauter, and M. Böni-Schnetzler, “Inflammation in obesity and diabetes: islet dysfunction and therapeutic opportunity,” Cell Metabolism, vol. 17, no. 6, pp. 860–872, 2013. View at Publisher · View at Google Scholar · View at Scopus
  24. R. Medzhitov, “Origin and physiological roles of inflammation,” Nature, vol. 454, no. 7203, pp. 428–435, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. T. S. Kern, “Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy,” Experimental Diabetes Research, vol. 2007, Article ID 95103, 14 pages, 2007. View at Publisher · View at Google Scholar · View at Scopus
  26. K. Mastej and R. Adamiec, “Neutrophil surface expression of CD11b and CD62L in diabetic microangiopathy,” Acta Diabetologica, vol. 45, no. 3, pp. 183–190, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. H. Xu, M. Chen, and J. V. Forrester, “Para-inflammation in the aging retina,” Progress in Retinal and Eye Research, vol. 28, no. 5, pp. 348–368, 2009. View at Publisher · View at Google Scholar · View at Scopus
  28. K. L. Heathcote, M. P. Wilson, D. W. Quest, and T. W. Wilson, “Prevalence and duration of exercise induced albuminuria in healthy people,” Clinical and Investigative Medicine, vol. 32, no. 4, pp. E261–E265, 2009. View at Google Scholar · View at Scopus