Research Article

Elevated Systemic Neutrophil Count Is Associated with Diabetic Macroalbuminuria among Elderly Chinese

Table 1

Demographic and clinical data of patients.

DiabetesAlbuminuria
DiabeticNondiabeticUA+UA

Subjects, 125410116411624
Mean age, y71 (65–76)70 (65–75)0.02170 (65–75)70 (65–75)0.0028
Gender, male/female721/932566/784NS266/375717/906NS
BMI, kg/m223.7 (21.4–26.0)23.9 (21.6–26.3)NS24.0 (21.8–26.5)23.6 (21.2–25.8)0.0012

Waist-hip ratio0.88 (0.84–0.91)0.88 (0.84–0.91)NS0.88 (0.84–0.91)0.87 (0.84–0.90)0.0002
SBP, mmHg132 (127–147)130 (125–142)0.0066133 (128–148)130 (124–140)<0.0001
DBP, mmHg80 (75–83)80 (76–83)NS80 (76–84)80 (74–81)0.0019
Hypertension774 (1254)568 (1011)0.0045384 (641)924 (1624)NS

ACE inhibitor73 (1254)39 (1011)0.000731 (641)60 (1624)NS
ARB197 (1254)128 (1011)0.021891 (641)222 (1624)NS
Total cholesterol, mmol/L5.8 (5.0–6.5)5.8 (5.1–6.5)NS5.8 (5.0–6.5)5.8 (5.1–6.5)NS
Triglycerides, mmol/L1.8 (1.3–2.4)1.8 (1.3–2.4)NS1.8 (1.3–2.4)1.7 (1.2–2.3)NS

FBG, mmol/L5.7 (5.3–7.4)5.8 (5.5–6.2)<0.00015.9 (5.4–6.6)5.8 (5.4–6.4)NS
Two-hour glucose, mmol/L8.4 (6.8–12.9)8.5 (7.9–9.3)0.00328.5 (7.2–10.7)8.4 (7.1–10.3)NS
SCr, mol/L69 (58–90)70 (60–81)NS70 (59–2)68.5 (60–78)0.0038
ALT, U/L21 (16–27)21 (17–28)NS21 (16–28)21 (16–27)NS

WBC, 109/L6.0 (5.1–7.0)5.9 (5.1–6.8)0.01386.0 (5.1–7.0)5.8 (5.0–6.8)0.0131
ANC, 109/L3.5 (2.8–4.3)3.3 (2.8–4.3)0.00013.4 (2.8–4.2)3.3 (2.7–4.0)<0.0001
ANC/WBC, %57.6 (50.8–63.9)56.3 (49.8–62.3)0.000758.0 (51.9–64.0)56.2 (50.8–62.3)0.0006
ACR, mg/g6.4 (0–20.8)3.2 (0–12.6)0.00029.2 (27–19.2)0<0.0001

Data are presented as median and 25th–75th percentile, unless otherwise noted.
ACE, angiotensin-converting enzyme; ARB, angiotensin receptor blocker; NS, not significant.