Elevated Systemic Neutrophil Count Is Associated with Diabetic Macroalbuminuria among Elderly Chinese
Table 1
Demographic and clinical data of patients.
Diabetes
Albuminuria
Diabetic
Nondiabetic
UA+
UA−
Subjects,
1254
1011
641
1624
Mean age, y
71 (65–76)
70 (65–75)
0.021
70 (65–75)
70 (65–75)
0.0028
Gender, male/female
721/932
566/784
NS
266/375
717/906
NS
BMI, kg/m2
23.7 (21.4–26.0)
23.9 (21.6–26.3)
NS
24.0 (21.8–26.5)
23.6 (21.2–25.8)
0.0012
Waist-hip ratio
0.88 (0.84–0.91)
0.88 (0.84–0.91)
NS
0.88 (0.84–0.91)
0.87 (0.84–0.90)
0.0002
SBP, mmHg
132 (127–147)
130 (125–142)
0.0066
133 (128–148)
130 (124–140)
<0.0001
DBP, mmHg
80 (75–83)
80 (76–83)
NS
80 (76–84)
80 (74–81)
0.0019
Hypertension
774 (1254)
568 (1011)
0.0045
384 (641)
924 (1624)
NS
ACE inhibitor
73 (1254)
39 (1011)
0.0007
31 (641)
60 (1624)
NS
ARB
197 (1254)
128 (1011)
0.0218
91 (641)
222 (1624)
NS
Total cholesterol, mmol/L
5.8 (5.0–6.5)
5.8 (5.1–6.5)
NS
5.8 (5.0–6.5)
5.8 (5.1–6.5)
NS
Triglycerides, mmol/L
1.8 (1.3–2.4)
1.8 (1.3–2.4)
NS
1.8 (1.3–2.4)
1.7 (1.2–2.3)
NS
FBG, mmol/L
5.7 (5.3–7.4)
5.8 (5.5–6.2)
<0.0001
5.9 (5.4–6.6)
5.8 (5.4–6.4)
NS
Two-hour glucose, mmol/L
8.4 (6.8–12.9)
8.5 (7.9–9.3)
0.0032
8.5 (7.2–10.7)
8.4 (7.1–10.3)
NS
SCr, mol/L
69 (58–90)
70 (60–81)
NS
70 (59–2)
68.5 (60–78)
0.0038
ALT, U/L
21 (16–27)
21 (17–28)
NS
21 (16–28)
21 (16–27)
NS
WBC, 109/L
6.0 (5.1–7.0)
5.9 (5.1–6.8)
0.0138
6.0 (5.1–7.0)
5.8 (5.0–6.8)
0.0131
ANC, 109/L
3.5 (2.8–4.3)
3.3 (2.8–4.3)
0.0001
3.4 (2.8–4.2)
3.3 (2.7–4.0)
<0.0001
ANC/WBC, %
57.6 (50.8–63.9)
56.3 (49.8–62.3)
0.0007
58.0 (51.9–64.0)
56.2 (50.8–62.3)
0.0006
ACR, mg/g
6.4 (0–20.8)
3.2 (0–12.6)
0.0002
9.2 (27–19.2)
0
<0.0001
Data are presented as median and 25th–75th percentile, unless otherwise noted. ACE, angiotensin-converting enzyme; ARB, angiotensin receptor blocker; NS, not significant.