Clinical Study

Cushing’s Disease: The Relevance of a Combined Dexamethasone Desmopressin Test as a Component of Postoperative Hormonal Evaluation

Table 1

Basic pre- and postoperative characteristics of the study group.

Age1 (years)36.1 ± 13.5
Males, (%)6 (21.4%)
BMI1 (kg/m2)29.6 ± 5.8
Preoperative plasma ACTH2 (pg/mL)86.0 (62.0–137.0)
Preoperative serum cortisol1 (µg/dL)26.7 ± 6.9
Serum cortisol after HDDST2 (µg/dL)3.9 (2.2–10.0)
Initial (1st) TSS, (%)21 (75.0%)
Tumor size, (%)
 Microadenoma23 (82.1%)
 Macroadenoma5 (17.9%)
Immunohistochemical confirmation of corticotroph tumor, (%)21 (75%)
Nadir serum cortisol2
on 1st or 2nd postoperative day (µg/dL)
2.3 (1.2–8.2)

Mean ± SD, 2median (interquartile range).