High Doses of Caffeine during the Peripubertal Period in the Rat Impair the Growth and Function of the Testis

Figure 3

Effect of caffeine on the weights of the testes in the control and caffeine-fed animals. (a) Absolute testes weight (g) and (b) relative testis weight to body weight (mg/g body weight) in the control and caffeine-fed groups at 4 weeks of caffeine exposure. Values are expressed as mean ± SD. versus CTRL. (c) Representative picture of the testes. From the left in order, testes representing each group are designated as CTRL, CF1, and CF2. CTRL, control; CF1, caffeine 120 mg/kg/day; CF2, caffeine 180 mg/kg/day.

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